Synthesis & Analysis Hub
The Pharmaceutical Chemistry Laboratory at Lakshmi Narain College of Pharmacy (LNCP), Indore provides comprehensive facilities for organic synthesis, drug design, spectroscopic analysis, and pharmaceutical chemistry research. Students gain practical experience in synthesis, purification, and characterization of pharmaceutical compounds using modern analytical instruments.
The lab supports both undergraduate and postgraduate research in medicinal chemistry, drug discovery, and computational chemistry.
Lab Sections
Organic Synthesis Lab
Multi-step organic synthesis setups, rotary evaporators, vacuum distillation units, microwave synthesizers, and fume hoods for safe handling of chemicals during synthesis of pharmaceutical intermediates and active compounds.
Instrumentation Lab
FT-IR spectrophotometer, UV-Vis double beam spectrophotometer, polarimeter, refractometer, melting point apparatus, and Karl Fischer titrator for characterization and purity analysis.
Computer-Aided Drug Design Lab
High-performance workstations with molecular docking software (AutoDock, Discovery Studio), QSAR tools, molecular dynamics simulation, and drug design software suites.
Green Chemistry Section
Microwave synthesis, ultrasound-assisted synthesis, and flow chemistry setups for environmentally sustainable chemical synthesis following green chemistry principles.
Major Equipment Specifications
| S.No. | Equipment | Specifications | Qty |
|---|---|---|---|
| 1 | FT-IR Spectrometer | 4000-400 cm&supmin;¹, ATR accessory, KBr pellet | 1 |
| 2 | UV-Vis Spectrophotometer | Double beam, 190-1100 nm, 1 nm resolution | 2 |
| 3 | Rotary Evaporator | 5L capacity, digital temperature, vacuum control | 3 |
| 4 | Microwave Synthesizer | 2.45 GHz, up to 300W, pressure control | 1 |
| 5 | Automatic Polarimeter | ±89.9° range, 589 nm LED | 1 |
| 6 | Digital Melting Point Apparatus | RT-400°C, 0.1°C resolution | 4 |
| 7 | Karl Fischer Titrator | Volumetric, 10 ppm to 100% water | 1 |
| 8 | HPLC System | Binary pump, DAD detector, auto-sampler | 1 |
| 9 | Molecular Modeling Workstation | 64GB RAM, NVIDIA GPU, Linux/Windows | 5 |
| 10 | Fume Hoods | Ducted, 1200mm, with monitoring system | 4 |
Software Resources
- AutoDock Vina / Schrödinger Suite (Molecular Docking)
- ChemDraw / Chem3D / MarvinSketch
- Discovery Studio / MOE (Molecular Modeling)
- Gaussian / ORCA (Quantum Chemistry)
Safety & Chemical Storage
- Chemical store with segregated storage (acids, bases, flammables)
- Emergency eyewash and safety shower stations
- Fire extinguisher and fire blanket availability
- Chemical waste disposal as per CPCB guidelines